THE BENEFITS OF CBD: FACT OR FICTION?
THE BENEFITS OF CBD: FACT OR FICTION?
Claims about the therapeutic possibility of CBD are universal online. The World Health Organization, like others, has confirmed the good safety profile of CBD, which poses no risk of abuse. More and more people around the world are asking their doctors if CBD could be a useful treatment for them. From capsules and oils to topical creams and oral sprays, the CBD craze has taken off. The best idea to use is green apple CBD gummies that help you stay healthy.
The study suggests that CBD-rich medical cannabis treatments alone result in only a modest improvement in symptoms.
Does the evidence for CBD's effectiveness back up the hype?
LIMITED EVIDENCE OF SYMPTOMS RELIEF
Cannabidiol, or CBD, is the primary cannabinoid found in hemp and is generally the second most common cannabinoid in the cannabis plant. More recently, under Canada's Medical Cannabis Access Program, cannabis strains and cannabis products for medical purposes have been developed to contain primarily CBD, although traces of THC and other cannabinoids are present.
CBD is known for its antiepileptic and anxiolytic effects supported by clinical and preclinical evidence. Numerous studies have also shown anti-inflammatory, antipsychotic, immunomodulatory, and neuroprotective special effects. Yet the mechanisms of CBD's effects remain poorly understood, and the lack of evidence supporting many of its potential therapeutic properties is proving to be a barrier to its clinical use.
Seizures related to refractory epilepsy are the symptoms for which there is the most indication assisting the use of CBD. The first CBD-based pharmaceutical product was approved by the US Food and Drug Administration (FDA) in 2018 as an anticonvulsant in the treatment of Lennox-Gastaut syndrome and Dravet syndrome. It was also approved by the European Medicines Agency in 2019 but is not available in Canada at this time.
Results from 5 randomized controlled trials also suggest moderate evidence that CBD may help reduce symptoms of psychosis.
Although the evidence supporting CBD as an anxiolytic is limited, clinicians have observed good results using CBD-rich treatments to relieve symptoms of anxiety. A recent increase in the number of long-term, high-quality studies on CBD and anxiety may offer more conclusive results over the next few years. However, mental disorders such as anxiety currently only account for about 6% of patient cases. You can use CBD oil for anxiety to stay healthy.
IF YOU WANT TO LEARN MORE ABOUT THE USE OF CBD AND CANNABIS-BASED MEDICAL TREATMENTS, SIGN UP FOR OUR DOCTOR TRAINING PROGRAM
CBD VS. CBD AND THC
CBD's popularity has grown in part due to its good safety profile and the fact that it does not cause the psychoactive effects typically associated with THC.
These characteristics have, to some extent, helped create the impression that CBD has greater medical and therapeutic value than THC. In some countries, authorities have even launched medical cannabis access programs that rely exclusively on CBD treatment plans.
The most recent clinical study by CBD Dietitian, however, suggests that CBD-rich treatments produce only limited improvements in symptom management, compared to treatment plans that combine both CBD and THC.
In some settings, the use of THC may sometimes be necessary for patients to derive more benefits from their medical cannabis treatment.
The study was to be presented at the annual symposium of the International Cannabinoid Research Society and will be published later this year.
It was conducted with patients who started medical treatment with cannabis in one of our four clinics in Quebec between 2017 and 2019. The study followed two groups during this period: a group of 715 patients to whom the CBD-rich treatments were prescribed and a group of 380 patients who were prescribed both THC and CBD treatments.
The effectiveness of the treatments was assessed using a standardized medical questionnaire and validated assessment tools such as the Edmonton Symptom Assessment Scale (ESAS) or green apple gummies, the Brief Pain Inventory (BPI), and EQ5D at baseline (BL), as well as follow-up at 3 months (FUP1) and 6 months (FUP2).
The study found that patients whose treatment plan relied solely on CBD products reported fewer improvements and benefits than those who incorporated both THC and CBD into their treatment. The group of patients who received both CBD and THC showed greater improvement for almost all items assessed, by a statistically and clinically significant margin.
Additional data and further investigation are still needed to further validate these results and to control for potential biases.
In the meantime, in the absence of results from other studies, it's probably best to approach the CBD craze with caution and perhaps a dose of skepticism. The best CBN oil for sleep, however, remains keen to pursue clinical research on the subject in cooperation with other participants in the scientific, pharmaceutical, and medical fields of cannabis.
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VIDEO AS A SALES TOOL: SOME EXAMPLES OF RESULTS
4 WAYS TO USE VIDEO AS A SALES TOOL
Video as a sales tool attracts attention and allows B2C and B2B companies to stand out.
As solicitations of all kinds multiply, it becomes important to be successful. And it is precisely for this reason that so many companies are betting on video with the help of a production company near me.
With this medium, you maximize your chances of being heard and succeeding with your conversion strategy. By the way, did you know that nearly 80% of people would rather watch a video than read a text?
Also, the video is:
human
Direct
Dynamic
Memorable
Adaptable for all platforms
Find out why integrating video content into your sales tools is a profitable strategy through a scriptwriter!
1. CREATE PERSONALIZED VIDEO MESSAGES
Imagine 2 different companies sending you a message to tell you about their services. One sends you generic and formatted content, while the other calls you by name and has created a video message adapted to your reality. It is obvious which of the two will have your attention!
This video content can be playful, or a little more classic, but, in any case, it must appeal to those you are targeting.
See how this data management company integrated the name of a prospect and their company into its messaging through the production companies near me.
2. EDUCATE YOUR PROSPECTS WITH VIDEO
Video content used as a sales tool can introduce your prospects to a new product, service, or process that they need to know about.
By using this type of video, you also demonstrate your expertise and give a good first impression to those you are targeting.
Here's an example of how you can introduce businesses to a new solution for their business.
3. MAKE A DEMO VIDEO
Why explain at length how easy it is to use your product/service when a video does it more effectively? At the same time, you reach both visual and auditory people.
It is possible to be dynamic and interesting while putting forward your best arguments! The video demonstrates it well with the assistance of one of the best video companies near me.
4. SHOWCASE CUSTOMER SATISFACTION WITH VIDEO
Sometimes the best way to prove your added value is to let your customers do the talking. Presenting video content that uses testimonials as a sales tool can have a big impact on generating leads.
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Are Cracks in New Home Foundations Normal?
Are Cracks in New Home Foundations Normal?
Foundation cracks in a home sometimes occur soon after the building is erected. They are a source of concern for many new owners. Are they right to be alarmed? This article demystifies for you the subject of cracks in the foundations of new houses through foundation repair Utah.
One foundation, two types of cracks
When it comes to cracks in the foundation of a new house, we mainly distinguish between two types.
Shrinkage cracks in new constructions
Building materials contain a good proportion of water. The concrete floor, basement walls, plaster, and wood of new construction alone initially contain about 4,000 liters of water. Most of this water will vanish during the first year of the structure’s life. This means that drying out of these materials occurs during this period. Although normal, this drying out can cause small cracks called shrinkage cracks.
These openings frequently originate under basement windows and above doorways. But, these cracks can also occur at lowered places and in the center of the walls if expansion joints have not been made.
When they appear on a poured concrete foundation wall, shrinkage cracks can be explained by poor mixing, too rapid curing, or inadequate steel reinforcement. Temperature variations, which bring about concrete to increase and contract, might also bring about small cracks.
In general, the repair of interior cracks on a concrete foundation does not require major repair work. At this time, you can wait a little longer before intervening until the foundation dries completely. Shrinkage cracks can be sealed easily to prevent water infiltration. A foundation crack contractor will inject a flexible polyurethane to cover the openings to do this. This technique guarantees the complete repair of the foundation.
Cracks brought about by ground movement under the new house
The second type of cracks that can appear on the foundation of a new house is explained by the movement of the ground. These cracks are often present in poured walls. Generally, they occur soon after the construction of the building is finished.
Frost, point loads, or clay soils are frequently the source of these irregular cracks. Soil conditions and materials used will dictate the hydraulic push piers type of repairs to correct this problem. At this point, new homeowners are right to be alarmed. To repair this type of foundation crack, the foundation of the building will need to be stabilized. At that time, major excavation work will have to be carried out. This work will usually be combined with waterproofing and basement drainage components to prevent the problem from recurring.
To put an end to foundation cracks on new homes
New homes are not immune to cracks, as are homes with older foundations. To maximize the lifespan of your home and to promote the health of the occupants, contact a Utah foundation repair. Its dedicated staff and cutting-edge expertise will ensure or restore the structural integrity of your building.
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Your Business in the United States: Predicting the Possible Impacts for Your Business
Your Business in the United States: Predicting the Possible Impacts for Your Business
The election of the new president, Democrat Joe Biden, will likely significantly change the US economic and fiscal environment.
Do you have business activities in the United States?
Do you own a property on American soil?
Stay on the lookout since the expected changes in tax legislation as well as in connection with the increase in protectionist measures could affect your operations, the profitability of your American business, and even your personal financial situation.
Therefore, it is more than relevant and necessary to surround yourself with US tax experts to help you target the tax strategies that will allow you to manage the opportunities, but also to avoid the risks that will emerge from this new presidency through M&A advisory.
ASSESS THE IMPACT ON YOUR OPERATIONS
Did you know that US corporate tax rates are likely to increase and reduce your profitability?
Indeed, the Biden plan calls for an increase in the corporate tax rate from 21% to 28%. Such an increase would bring US corporate tax rates to levels higher than those applicable in Canada. In order to lessen the impact on your bottom line, it, therefore, becomes essential that your business be structured in such a way as to reduce or eliminate Uncle Sam's federal tax liability by taking mergers and acquisitions services.
Indeed, if your company pays taxes in the United States, your tax specialist can help you adapt your structure in order to pay less taxes overall. For example, if your taxable income is $1 million, 80% of which is generated in the American company, it would be relevant to analyze the tactics that would make it possible to transfer a portion of the income to the Canadian company and thus limit the impact tax.
On the other hand, if you do business in the United States using a pure export strategy, the possible application of protectionist measures such as the “Buy American Act” can confuse, or even remove, your ability to sell to your American clientele with your existing business model.
Whatever your situation, your US tax expert will be able to assist you in implementing the best possible strategy. For example, in order to avoid compromising the financial situation of your business or reducing its future assets, it could, among other things, direct you towards:
the creation of an American company allowing you to circumvent protectionist measures;
the diversification of your international customers in order to reduce your dependence on the United States.
ASSESS THE IMPACT ON YOUR PERSONAL
If you own one or more properties in the United States, whether for investment purposes or simply for you and your family, the tax changes anticipated following the election of Joe Biden could have a significant financial impact.
The anticipated increase in the top marginal individual tax rate from 37% to 39.6% as well as the elimination of preferential rates for large capital gains will affect the financial profitability of your US real estate investment.
In addition, in the event of death, the likely reduction in the estate tax exemption ceilings and the increase in the applicable rates will result in the payment of estate tax for many Canadians with property in the United States or securities of US public companies. Currently, Canadians whose worldwide estate value at death does not exceed US$11.7 million are not at risk of having their estate reduced by these estate taxes. Under the Biden administration, this threshold could be reduced to US$3.5 million.
In light of this information, have you assessed the suitability of transferring your U.S. real estate ownership to a trust?
Your tax specialist can help you see this more clearly.
KEEP YOUR TAX
The pandemic has had the effect of significantly increasing the US public debt. Thus, over the next few years, the US federal government, and the states in general, will have to find additional sources of revenue in order to reduce this debt.
Subsequently, tax audits targeting foreign companies may be on the increase; what could be better for a government than to increase its tax receipts by stealing from foreign corporations that are not owned by their constituents?
What to do? Be sure to update your tax compliance to avoid any unpleasant surprises in the event of an audit by the US tax authorities.
Have you checked that:
your sales are not subject to US sales tax?
your income is not subject to US taxes?
Rely on the advice of an expert in the field to ensure that your tax compliance is up to date while optimizing your financial portfolio.
Be proactive. By consulting an M&A advisor in American taxation, you will be able to adapt your operational and sales structures in order to maintain and maximize your profitability for the good continuity of your American business. In addition, if you have invested in real estate in the United States, it is important to know how to minimize the impact of possible measures on the value of your investments.
The experts are well equipped and ready to provide leadership coaching services to support you in this phase of questioning and uncertainty. In addition, thanks to the scope of our professional services, we will be able to offer you complete support if needs arise in terms of strategic planning, optimization of the business model, purchase, or sale of a business.
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Booster Dose and Omicron
Yes, I know you are tired. You know what? Me too.
That said, our dear favorite coronavirus has nothing to do with it and it continues to multiply and mutate. The last variant in the running is Omicron, which represents the dominant strain in San Diego and around the world. We have seen in recent weeks its great contagiousness through psych evaluation near me.
This characteristic makes that, despite its lower virulence, many people collect themselves in the hospital despite everything considering the very high number of cases. Another thing characterizes it: its Spike protein, the target of the antibodies produced by current vaccines, has mutated and these antibodies have a lower affinity for their target.
That said, despite what the anti-vax like to claim, the vaccine is still the weapon of choice to prevent complications and serious illness, because immunity is not just a question of antibodies. Indeed, the data confirms to us that two doses of vaccine are of little or no effect in preventing contracting the disease, but offer 50-60% protection against complications (such as hospitalization).
Now, what does a booster dose do? It makes it possible to reproduce one of the antibodies which, by their very large quantity, will succeed in binding to the Spike protein despite the lower affinity. This results in protection of 60-70% to prevent the contraction of the disease and about 90% against complications. These results are excellent!
I feel a shortness of breath in the vaccination of the third dose and it worries me because I too am looking forward to returning to a normal life. And whether we agree or not, the decisions of Public Health are directly linked to the situation in hospitals. The only way to lessen the COVID-induced strain on our psychological healthcare system is to get your booster shot.
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